Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1

Bromodomain and extraterminal domain (BET) proteins, which are important epigenetic readers, are often dysregulated in cancer. While a number of BET inhibitors are currently in early phase clinical trials, BET inhibitors show limited single-agent activity. The purpose of this study is to determine i...

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Detalles Bibliográficos
Autores principales: Pham, Thao N.D., Stempel, Sophie, Shields, Mario A., Spaulding, Christina, Kumar, Krishan, Bentrem, David J., Matsangou, Maria, Munshi, Hidayatullah G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747365/
https://www.ncbi.nlm.nih.gov/pubmed/31480735
http://dx.doi.org/10.3390/ijms20174293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747365/
https://www.ncbi.nlm.nih.gov/pubmed/31480735
http://dx.doi.org/10.3390/ijms20174293

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