Mismatch Recognition by Saccharomyces cerevisiae Msh2-Msh6: Role of Structure and Dynamics

The mismatch repair (MMR) pathway maintains genome integrity by correcting errors such as mismatched base pairs formed during DNA replication. In MMR, Msh2–Msh6, a heterodimeric protein, targets single base mismatches and small insertion/deletion loops for repair. By incorporating the fluorescent nu...

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Detalles Bibliográficos
Autores principales: Li, Yan, Lombardo, Zane, Joshi, Meera, Hingorani, Manju M., Mukerji, Ishita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747400/
https://www.ncbi.nlm.nih.gov/pubmed/31480444
http://dx.doi.org/10.3390/ijms20174271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747400/
https://www.ncbi.nlm.nih.gov/pubmed/31480444
http://dx.doi.org/10.3390/ijms20174271

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