A Cyclic Pentamethinium Salt Induces Cancer Cell Cytotoxicity through Mitochondrial Disintegration and Metabolic Collapse

Cancer cells preferentially utilize glycolysis for ATP production even in aerobic conditions (the Warburg effect) and adapt mitochondrial processes to their specific needs. Recent studies indicate that altered mitochondrial activities in cancer represent an actionable target for therapy. We previous...

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Detalles Bibliográficos
Autores principales: Krejcir, Radovan, Krcova, Lucie, Zatloukalova, Pavlina, Briza, Tomas, Coates, Philip J., Sterba, Martin, Muller, Petr, Kralova, Jarmila, Martasek, Pavel, Kral, Vladimir, Vojtesek, Borivoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747461/
https://www.ncbi.nlm.nih.gov/pubmed/31466233
http://dx.doi.org/10.3390/ijms20174208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747461/
https://www.ncbi.nlm.nih.gov/pubmed/31466233
http://dx.doi.org/10.3390/ijms20174208

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