Antifibrotic Effects of High-Mobility Group Box 1 Protein Inhibitor (Glycyrrhizin) on Keloid Fibroblasts and Keloid Spheroids through Reduction of Autophagy and Induction of Apoptosis

Overabundance of extracellular matrix resulting from hyperproliferation of keloid fibroblasts (KFs) and dysregulation of apoptosis represents the main pathophysiology underlying keloids. High-mobility group box 1 (HMGB1) plays important roles in the regulation of cellular death. Suppression of HMGB1...

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Detalles Bibliográficos
Autores principales: Jeon, Yeo Reum, Roh, Hyun, Jung, Ji Hyuk, Ahn, Hyo Min, Lee, Ju Hee, Yun, Chae-Ok, Lee, Won Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747471/
https://www.ncbi.nlm.nih.gov/pubmed/31450620
http://dx.doi.org/10.3390/ijms20174134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747471/
https://www.ncbi.nlm.nih.gov/pubmed/31450620
http://dx.doi.org/10.3390/ijms20174134

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