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Cortical Seizures in FoxG1(+/−) Mice are Accompanied by Akt/S6 Overactivation, Excitation/Inhibition Imbalance and Impaired Synaptic Transmission

The correct morphofunctional shaping of the cerebral cortex requires a continuous interaction between intrinsic (genes/molecules expressed within the tissue) and extrinsic (e.g., neural activity) factors at all developmental stages. Forkhead Box G1 (FOXG1) is an evolutionarily conserved transcriptio...

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Detalles Bibliográficos
Autores principales: Testa, Giovanna, Olimpico, Francesco, Pancrazi, Laura, Borello, Ugo, Cattaneo, Antonino, Caleo, Matteo, Costa, Mario, Mainardi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747530/
https://www.ncbi.nlm.nih.gov/pubmed/31450553
http://dx.doi.org/10.3390/ijms20174127