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Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA

A defining characteristic of treating tuberculosis is the need for prolonged administration of multiple drugs. This may be due in part to subpopulations of slowly replicating or nonreplicating Mycobacterium tuberculosis bacilli exhibiting phenotypic tolerance to most antibiotics in the standard trea...

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Detalles Bibliográficos
Autores principales: Lopez Quezada, Landys, Silve, Sandra, Kelinske, Mark, Liba, Amir, Diaz Gonzalez, Constantino, Kotev, Martin, Goullieux, Laurent, Sans, Stephanie, Roubert, Christine, Lagrange, Sophie, Bacqué, Eric, Couturier, Cedric, Pellet, Alain, Blanc, Isabelle, Ferron, Marlène, Debu, Fabrice, Li, Kelin, Aubé, Jeffrey, Roberts, Julia, Little, David, Ling, Yan, Zhang, Jun, Gold, Ben, Nathan, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747715/
https://www.ncbi.nlm.nih.gov/pubmed/31289182
http://dx.doi.org/10.1128/mBio.01405-19