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The Extracellular Domain of the β(2) Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity

The Escherichia coli hemolysin (HlyA) is a pore-forming exotoxin associated with severe complications of human urinary tract infections. HlyA is the prototype of the repeats-in-toxin (RTX) family, which includes LtxA from Aggregatibacter actinomycetemcomitans, a periodontal pathogen. The existence a...

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Detalles Bibliográficos
Autores principales: Ristow, Laura C., Tran, Vy, Schwartz, Kevin J., Pankratz, Lillie, Mehle, Andrew, Sauer, John-Demian, Welch, Rodney A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747720/
https://www.ncbi.nlm.nih.gov/pubmed/31289186
http://dx.doi.org/10.1128/mBio.01459-19