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Sirtuin Inhibitors Are Broadly Antiviral against Arboviruses
Arthropod-borne viruses are diverse pathogens and are often associated with human disease. These viruses span multiple genera, including flaviviruses, alphaviruses, and bunyaviruses. In a high-throughput drug screen, we found that tenovin-1 was antiviral against the flaviviruses Zika virus and dengu...
Autores principales: | Hackett, Brent A., Dittmar, Mark, Segrist, Elisha, Pittenger, Nathan, To, Julie, Griesman, Trevor, Gordesky-Gold, Beth, Schultz, David C., Cherry, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747726/ https://www.ncbi.nlm.nih.gov/pubmed/31289184 http://dx.doi.org/10.1128/mBio.01446-19 |
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