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Persistent DNA Damage Foci and DNA Replication with a Broken Chromosome in the African Trypanosome

Damaged DNA typically imposes stringent controls on eukaryotic cell cycle progression, ensuring faithful transmission of genetic material. Some DNA breaks, and the resulting rearrangements, are advantageous, however. For example, antigenic variation in the parasitic African trypanosome, Trypanosoma...

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Detalles Bibliográficos
Autores principales: Glover, Lucy, Marques, Catarina A., Suska, Olga, Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747728/
https://www.ncbi.nlm.nih.gov/pubmed/31289179
http://dx.doi.org/10.1128/mBio.01252-19