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Preactivation of Notch1 in remote ischemic preconditioning reduces cerebral ischemia-reperfusion injury through crosstalk with the NF-κB pathway

BACKGROUND: Remote ischemic preconditioning (RIPC) initiates endogenous protective pathways in the brain from a distance and represents a new, promising paradigm in neuroprotection against cerebral ischemia-reperfusion (I/R) injury. However, the underlying mechanism of RIPC-mediated cerebral ischemi...

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Detalles Bibliográficos
Autores principales: Liang, Weidong, Lin, Chunshui, Yuan, Liuqing, Chen, Li, Guo, Peipei, Li, Ping, Wang, Wei, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747758/
https://www.ncbi.nlm.nih.gov/pubmed/31526384
http://dx.doi.org/10.1186/s12974-019-1570-9