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PDMS-PMOXA-Nanoparticles Featuring a Cathepsin B-Triggered Release Mechanism
Background: It was our intention to develop cathepsin B-sensitive nanoparticles for tumor-site-directed release. These nanoparticles should be able to release their payload as close to the tumor site with a decrease of off-target effects in mind. Cathepsin B, a lysosomal cysteine protease, is associ...
Autores principales: | Ehrsam, Daniel, Porta, Fabiola, Hussner, Janine, Seibert, Isabell, Meyer zu Schwabedissen, Henriette E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747961/ https://www.ncbi.nlm.nih.gov/pubmed/31484396 http://dx.doi.org/10.3390/ma12172836 |
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