Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

Drug resistance imposes severe limitations to the efficacy of targeted therapy in BRAF-mutated metastatic melanoma. Although this issue has been mitigated by the development of combination therapies with BRAF plus MEK inhibitors, drug resistance inevitably occurs with time and results in clinical re...

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Detalles Bibliográficos
Autores principales: Fattore, Luigi, Ruggiero, Ciro Francesco, Pisanu, Maria Elena, Liguoro, Domenico, Cerri, Andrea, Costantini, Susan, Capone, Francesca, Acunzo, Mario, Romano, Giulia, Nigita, Giovanni, Mallardo, Domenico, Ragone, Concetta, Carriero, Maria Vincenza, Budillon, Alfredo, Botti, Gerardo, Ascierto, Paolo Antonio, Mancini, Rita, Ciliberto, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748102/
https://www.ncbi.nlm.nih.gov/pubmed/30254376
http://dx.doi.org/10.1038/s41418-018-0205-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748102/
https://www.ncbi.nlm.nih.gov/pubmed/30254376
http://dx.doi.org/10.1038/s41418-018-0205-5

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