Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation

RASSF1A (Ras association domain family 1 isoform A) is a tumor suppressor and frequently inactivated by promoter hypermethylation in hepatocellular carcinoma (HCC). Autophagy is to degrade misfolded or aggregated proteins and dysfunctional organelles. Autophagy defects enhance oxidative stress and g...

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Detalles Bibliográficos
Autores principales: Li, Wenjiao, Yue, Fei, Dai, Yuan, Shi, Boyun, Xu, Guibin, Jiang, Xianhan, Zhou, Xinke, Pfeifer, Gerd P., Liu, Leyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748129/
https://www.ncbi.nlm.nih.gov/pubmed/30315205
http://dx.doi.org/10.1038/s41418-018-0211-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748129/
https://www.ncbi.nlm.nih.gov/pubmed/30315205
http://dx.doi.org/10.1038/s41418-018-0211-7

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