BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL

BFL1 is a relatively understudied member of the BCL2 protein family which has been implicated in the pathogenesis and chemoresistance of a variety of human cancers, including hematological malignancies and solid tumours. BFL1 is generally considered to have an antiapoptotic function, although its pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Flores-Romero, Hector, Landeta, Olatz, Ugarte-Uribe, Begoña, Cosentino, Katia, García-Porras, Miguel, García-Sáez, Ana J., Basañez, Gorka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748131/
https://www.ncbi.nlm.nih.gov/pubmed/30560933
http://dx.doi.org/10.1038/s41418-018-0258-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748131/
https://www.ncbi.nlm.nih.gov/pubmed/30560933
http://dx.doi.org/10.1038/s41418-018-0258-5

Ejemplares similares