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BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation

Hypoxia inducible factor 1α (HIF1α) is a master regulator leading to metabolic adaptation, an essential physiological process to maintain the survival of stem cells under hypoxia. However, it is poorly understood how HIF1α translocates into the nucleus in stem cells under hypoxia. Here, we investiga...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Jik, Jung, Young Hyun, Oh, Ji Young, Choi, Gee Euhn, Chae, Chang Woo, Kim, Jun Sung, Lim, Jae Ryong, Kim, Seo Yihl, Lee, Sei-Jung, Seong, Je Kyung, Han, Ho Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748134/
https://www.ncbi.nlm.nih.gov/pubmed/30464225
http://dx.doi.org/10.1038/s41418-018-0241-1