PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency

The serine/threonine phosphatase PP4 has been implicated in DNA damage repair and cell cycle regulation through its dephosphorylation of specific substrates. We previously showed that PP4 is required for mouse B cell development, germinal center (GC) formation and immunoglobulin (Ig) class switch re...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ming-Yu, Hsu, Wei-Chan, Hsu, Shu-Ching, Yang, Yu-Shao, Chuang, Tsung-Hsien, Lin, Wen-Jye, Tan, Tse-Hua, Su, Yu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748143/
https://www.ncbi.nlm.nih.gov/pubmed/30237510
http://dx.doi.org/10.1038/s41418-018-0199-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748143/
https://www.ncbi.nlm.nih.gov/pubmed/30237510
http://dx.doi.org/10.1038/s41418-018-0199-z

Ejemplares similares