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Oncogenic zinc finger protein ZNF322A promotes stem cell-like properties in lung cancer through transcriptional suppression of c-Myc expression

ZNF322A, a C2H2 zinc finger transcription factor, is an oncoprotein in lung cancer. However, the transcription mechanisms of ZNF322A in lung cancer stem cell-like reprogramming remain elusive. By integrating our chromatin immunoprecipitation-sequencing and RNA-sequencing datasets, we identified and...

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Detalles Bibliográficos
Autores principales: Jen, Jayu, Liu, Chun-Yen, Chen, Yu-Ting, Wu, Li-Ting, Shieh, Yang-Chih, Lai, Wu-Wei, Wang, Yi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748145/
https://www.ncbi.nlm.nih.gov/pubmed/30258097
http://dx.doi.org/10.1038/s41418-018-0204-6