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Mutant p53-dependent mitochondrial metabolic alterations in a mesenchymal stem cell-based model of progressive malignancy

It is well accepted that malignant transformation is associated with unique metabolism. Malignant transformation involves a variety of cellular pathways that are associated with initiation and progression of the malignant process that remain to be deciphered still. Here we used a mouse model of muta...

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Detalles Bibliográficos
Autores principales: Lonetto, Giuseppe, Koifman, Gabriela, Silberman, Alon, Attery, Ayush, Solomon, Hilla, Levin-Zaidman, Smadar, Goldfinger, Naomi, Porat, Ziv, Erez, Ayelet, Rotter, Varda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748146/
https://www.ncbi.nlm.nih.gov/pubmed/30413783
http://dx.doi.org/10.1038/s41418-018-0227-z