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Systems Biology-Based Analysis Indicates Global Transcriptional Impairment in Lead-Treated Human Neural Progenitor Cells

Lead poisoning effects are wide and include nervous system impairment, peculiarly during development, leading to neural damage. Lead interaction with calcium and zinc-containing metalloproteins broadly affects cellular metabolism since these proteins are related to intracellular ion balance, activat...

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Detalles Bibliográficos
Autores principales: Reis, Clovis F., de Souza, Iara D., Morais, Diego A. A., Oliveira, Raffael A. C., Imparato, Danilo O., de Almeida, Rita M. C., Dalmolin, Rodrigo J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748217/
https://www.ncbi.nlm.nih.gov/pubmed/31552095
http://dx.doi.org/10.3389/fgene.2019.00791