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Gene Editing Preserves Visual Functions in a Mouse Model of Retinal Degeneration

Inherited retinal dystrophies (IRDs) are a large and heterogeneous group of degenerative diseases caused by mutations in various genes. Given the favorable anatomical and immunological characteristics of the eye, gene therapy holds great potential for their treatment. Our goal is to validate the pre...

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Detalles Bibliográficos
Autores principales: Vagni, Paola, Perlini, Laura E., Chenais, Naïg A. L., Marchetti, Tommaso, Parrini, Martina, Contestabile, Andrea, Cancedda, Laura, Ghezzi, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748340/
https://www.ncbi.nlm.nih.gov/pubmed/31551698
http://dx.doi.org/10.3389/fnins.2019.00945