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Bioenergetics and Autophagic Imbalance in Patients-Derived Cell Models of Parkinson Disease Supports Systemic Dysfunction in Neurodegeneration

Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder worldwide affecting 2–3% of the population over 65 years. This prevalence is expected to rise as life expectancy increases and diagnostic and therapeutic protocols improve. PD encompasses a multitude of clinical, geneti...

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Detalles Bibliográficos
Autores principales: González-Casacuberta, Ingrid, Juárez-Flores, Diana Luz, Morén, Constanza, Garrabou, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748355/
https://www.ncbi.nlm.nih.gov/pubmed/31551675
http://dx.doi.org/10.3389/fnins.2019.00894