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R40.76 binds to the α domain of ZO-1: role of ZO-1 (α+) in epithelial differentiation and mechano-sensing

The barrier function of epithelia and endothelia depends on tight junctions, which are formed by the polymerization of claudins on a scaffold of ZO proteins. Two differentially spliced isoforms of ZO-1 have been described, depending on the presence of the α domain, but the function of this domain is...

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Detalles Bibliográficos
Autores principales: Rouaud, Florian, Vasileva, Ekaterina, Spadaro, Domenica, Tsukita, Sachiko, Citi, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748370/
https://www.ncbi.nlm.nih.gov/pubmed/31438766
http://dx.doi.org/10.1080/21688370.2019.1653748