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Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats

This study aimed to assess the renopreventive effect of enalapril and/or paricalcitol on streptozotocin (STZ) diabetes-induced nephropathy and to elucidate their mechanisms of action through investigation of the effects on renal oxidative stress, antioxidant defense system and expressions of TNF-α,...

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Detalles Bibliográficos
Autores principales: Ahmed, Osama M., Ali, Tarek M., Abdel Gaid, Mohamed A., Elberry, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748411/
https://www.ncbi.nlm.nih.gov/pubmed/31527864
http://dx.doi.org/10.1371/journal.pone.0214349