PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age

BACKGROUND: PNPLA3 rs738409 minor allele c.444G represents a risk factor for liver steatosis and fibrosis progression also in chronic hepatitis C (HCV). We investigated its impact on the timing of liver transplantation (LT) in patients with genotype 1b HCV cirrhosis. METHODS: We genotyped and evalua...

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Detalles Bibliográficos
Autores principales: Senkerikova, Renata, Frankova, Sona, Jirsa, Milan, Kreidlova, Miluse, Merta, Dusan, Neroldova, Magdalena, Chmelova, Klara, Spicak, Julius, Sperl, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748417/
https://www.ncbi.nlm.nih.gov/pubmed/31527889
http://dx.doi.org/10.1371/journal.pone.0222609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748417/
https://www.ncbi.nlm.nih.gov/pubmed/31527889
http://dx.doi.org/10.1371/journal.pone.0222609

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