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PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age
BACKGROUND: PNPLA3 rs738409 minor allele c.444G represents a risk factor for liver steatosis and fibrosis progression also in chronic hepatitis C (HCV). We investigated its impact on the timing of liver transplantation (LT) in patients with genotype 1b HCV cirrhosis. METHODS: We genotyped and evalua...
Autores principales: | Senkerikova, Renata, Frankova, Sona, Jirsa, Milan, Kreidlova, Miluse, Merta, Dusan, Neroldova, Magdalena, Chmelova, Klara, Spicak, Julius, Sperl, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748417/ https://www.ncbi.nlm.nih.gov/pubmed/31527889 http://dx.doi.org/10.1371/journal.pone.0222609 |
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