Pleiotropic role of Drosophila phosphoribosyl pyrophosphate synthetase in autophagy and lysosome homeostasis

Phosphoribosyl pyrophosphate synthetase (PRPS) is a rate-limiting enzyme whose function is important for the biosynthesis of purines, pyrimidines, and pyridines. Importantly, while missense mutations of PRPS1 have been identified in neurological disorders such as Arts syndrome, how they contribute t...

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Detalles Bibliográficos
Autores principales: Delos Santos, Keemo, Kim, Minhee, Yergeau, Christine, Jean, Steve, Moon, Nam-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748441/
https://www.ncbi.nlm.nih.gov/pubmed/31487280
http://dx.doi.org/10.1371/journal.pgen.1008376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748441/
https://www.ncbi.nlm.nih.gov/pubmed/31487280
http://dx.doi.org/10.1371/journal.pgen.1008376

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