Single-molecule correlated chemical probing reveals large-scale structural communication in the ribosome and the mechanism of the antibiotic spectinomycin in living cells

The ribosome moves between distinct structural states and is organized into multiple functional domains. Here, we examined hundreds of occurrences of pairwise through-space communication between nucleotides in the ribosome small subunit RNA using RNA interaction groups analyzed by mutational profili...

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Detalles Bibliográficos
Autores principales: Sengupta, Arnab, Rice, Greggory M., Weeks, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748448/
https://www.ncbi.nlm.nih.gov/pubmed/31487286
http://dx.doi.org/10.1371/journal.pbio.3000393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748448/
https://www.ncbi.nlm.nih.gov/pubmed/31487286
http://dx.doi.org/10.1371/journal.pbio.3000393

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