Influence of the bispecific antibody IgG subclass on T cell redirection

T cell redirection mediated by bispecific antibodies (BsAbs) is a promising cancer therapy. Dual antigen binding is necessary for potent T cell redirection and is influenced by the structural characteristics of a BsAb, which are dependent on its IgG subclass. In this study, model BsAbs targeting CD1...

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Detalles Bibliográficos
Autores principales: Kapelski, Stephanie, Cleiren, Erna, Attar, Ricardo M., Philippar, Ulrike, Häsler, Julien, Chiu, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748600/
https://www.ncbi.nlm.nih.gov/pubmed/31242061
http://dx.doi.org/10.1080/19420862.2019.1624464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748600/
https://www.ncbi.nlm.nih.gov/pubmed/31242061
http://dx.doi.org/10.1080/19420862.2019.1624464

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