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Microtubules Gate Tau Condensation to Spatially Regulate Microtubule Functions
Tau is an abundant microtubule-associated protein in neurons. Tau aggregation into insoluble fibrils is a hallmark of Alzheimer’s disease and other dementias(1), yet the physiological state of tau molecules within cells remains unclear. Using single molecule imaging, we directly observe that the mic...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748660/ https://www.ncbi.nlm.nih.gov/pubmed/31481790 http://dx.doi.org/10.1038/s41556-019-0375-5 |