Cargando…

Copper Hydride Catalyzed Enantioselective Synthesis of Axially Chiral 1,3-Disubstituted Allenes

[Image: see text] The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral starting materials remains a long-standing challenge in organic synthesis. Here, we report an efficient enantio- and chemoselective copper hydride catalyzed semireduction of conjugated eny...

Descripción completa

Detalles Bibliográficos
Autores principales: Bayeh-Romero, Liela, Buchwald, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748664/
https://www.ncbi.nlm.nih.gov/pubmed/31423768
http://dx.doi.org/10.1021/jacs.9b07582