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Copper Hydride Catalyzed Enantioselective Synthesis of Axially Chiral 1,3-Disubstituted Allenes
[Image: see text] The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral starting materials remains a long-standing challenge in organic synthesis. Here, we report an efficient enantio- and chemoselective copper hydride catalyzed semireduction of conjugated eny...
Autores principales: | Bayeh-Romero, Liela, Buchwald, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748664/ https://www.ncbi.nlm.nih.gov/pubmed/31423768 http://dx.doi.org/10.1021/jacs.9b07582 |
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