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KOnezumi: a web application for automating gene disruption strategies to generate knockout mice

SUMMARY: Although gene editing using the CRISPR/Cas9 system enables the rapid generation of knockout mice, constructing an optimal gene disruption strategy is still labourious. Here, we propose KOnezumi, a simple and user-friendly web application, for use in automating the design of knockout strateg...

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Detalles Bibliográficos
Autores principales: Kuno, Akihiro, Mizuno, Seiya, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748778/
https://www.ncbi.nlm.nih.gov/pubmed/30726877
http://dx.doi.org/10.1093/bioinformatics/btz090