Pharmacological inhibition of Notch signaling regresses pre-established abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is characterized by transmural infiltration of myeloid cells at the vascular injury site. Previously, we reported preventive effects of Notch deficiency on the development of AAA by reduction of infiltrating myeloid cells. In this study, we examined if Notch inhibitio...

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Detalles Bibliográficos
Autores principales: Sharma, Neekun, Dev, Rishabh, Ruiz-Rosado, Juan de Dios, Partida-Sanchez, Santiago, Guerau-de-Arellano, Mireia, Dhakal, Pramod, Kuivaniemi, Helena, Hans, Chetan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748927/
https://www.ncbi.nlm.nih.gov/pubmed/31530833
http://dx.doi.org/10.1038/s41598-019-49682-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748927/
https://www.ncbi.nlm.nih.gov/pubmed/31530833
http://dx.doi.org/10.1038/s41598-019-49682-0

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