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Pharmacological inhibition of Notch signaling regresses pre-established abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) is characterized by transmural infiltration of myeloid cells at the vascular injury site. Previously, we reported preventive effects of Notch deficiency on the development of AAA by reduction of infiltrating myeloid cells. In this study, we examined if Notch inhibitio...
Autores principales: | Sharma, Neekun, Dev, Rishabh, Ruiz-Rosado, Juan de Dios, Partida-Sanchez, Santiago, Guerau-de-Arellano, Mireia, Dhakal, Pramod, Kuivaniemi, Helena, Hans, Chetan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748927/ https://www.ncbi.nlm.nih.gov/pubmed/31530833 http://dx.doi.org/10.1038/s41598-019-49682-0 |
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