Within-host evolution of bovine Staphylococcus aureus selects for a SigB-deficient pathotype characterized by reduced virulence but enhanced proteolytic activity and biofilm formation

Staphylococcus aureus is a major cause of bovine mastitis, commonly leading to long-lasting, persistent and recurrent infections. Thereby, S. aureus constantly refines and permanently adapts to the bovine udder environment. In this work, we followed S. aureus within-host adaptation over the course o...

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Detalles Bibliográficos
Autores principales: Marbach, Helene, Mayer, Katharina, Vogl, Claus, Lee, Jean Y. H., Monk, Ian R., Sordelli, Daniel O., Buzzola, Fernanda R., Ehling-Schulz, Monika, Grunert, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748969/
https://www.ncbi.nlm.nih.gov/pubmed/31530887
http://dx.doi.org/10.1038/s41598-019-49981-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748969/
https://www.ncbi.nlm.nih.gov/pubmed/31530887
http://dx.doi.org/10.1038/s41598-019-49981-6

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