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Within-host evolution of bovine Staphylococcus aureus selects for a SigB-deficient pathotype characterized by reduced virulence but enhanced proteolytic activity and biofilm formation
Staphylococcus aureus is a major cause of bovine mastitis, commonly leading to long-lasting, persistent and recurrent infections. Thereby, S. aureus constantly refines and permanently adapts to the bovine udder environment. In this work, we followed S. aureus within-host adaptation over the course o...
Autores principales: | Marbach, Helene, Mayer, Katharina, Vogl, Claus, Lee, Jean Y. H., Monk, Ian R., Sordelli, Daniel O., Buzzola, Fernanda R., Ehling-Schulz, Monika, Grunert, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748969/ https://www.ncbi.nlm.nih.gov/pubmed/31530887 http://dx.doi.org/10.1038/s41598-019-49981-6 |
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