Estimating the Frequency of Single Point Driver Mutations across Common Solid Tumours

For cancers, such as common solid tumours, variants in the genome give a selective growth advantage to certain cells. It has recently been argued that the mean count of coding single nucleotide variants acting as disease-drivers in common solid tumours is frequently small in size, but significantly...

Descripción completa

Detalles Bibliográficos
Autores principales: Darbyshire, Madeleine, du Toit, Zachary, Rogers, Mark F., Gaunt, Tom R., Campbell, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748970/
https://www.ncbi.nlm.nih.gov/pubmed/31530827
http://dx.doi.org/10.1038/s41598-019-48765-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748970/
https://www.ncbi.nlm.nih.gov/pubmed/31530827
http://dx.doi.org/10.1038/s41598-019-48765-2

Ejemplares similares