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Estimating the Frequency of Single Point Driver Mutations across Common Solid Tumours
For cancers, such as common solid tumours, variants in the genome give a selective growth advantage to certain cells. It has recently been argued that the mean count of coding single nucleotide variants acting as disease-drivers in common solid tumours is frequently small in size, but significantly...
Autores principales: | Darbyshire, Madeleine, du Toit, Zachary, Rogers, Mark F., Gaunt, Tom R., Campbell, Colin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748970/ https://www.ncbi.nlm.nih.gov/pubmed/31530827 http://dx.doi.org/10.1038/s41598-019-48765-2 |
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