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Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice

Regulatory T cells (Tregs) are a double-edged regulator of the immune system. Aberrations of Tregs correlate with pathogenesis of inflammatory, autoimmune and neoplastic disorders. Phenotypically and functionally distinct subsets of Tregs have been identified in humans and mice on the basis of their...

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Detalles Bibliográficos
Autores principales: Wu, Ying, Chang, Yu-Mei, Stell, Anneliese J., Priestnall, Simon L., Sharma, Eshita, Goulart, Michelle R., Gribben, John, Xia, Dong, Garden, Oliver A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748983/
https://www.ncbi.nlm.nih.gov/pubmed/31530890
http://dx.doi.org/10.1038/s41598-019-50065-8