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Aggregated NETs Sequester and Detoxify Extracellular Histones

In response to various infectious and sterile stimuli neutrophils release chromatin decorated with bactericidal proteins, referred to as NETs. Their scaffolds are formed from chromatin fibers which display an apparent diameter of 15–17 nm and mainly consist from DNA (2 nm) and DNA-associated histone...

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Detalles Bibliográficos
Autores principales: Knopf, Jasmin, Leppkes, Moritz, Schett, Georg, Herrmann, Martin, Muñoz, Luis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749074/
https://www.ncbi.nlm.nih.gov/pubmed/31572386
http://dx.doi.org/10.3389/fimmu.2019.02176