Trypanosoma brucei Secreted Aromatic Ketoacids Activate the Nrf2/HO-1 Pathway and Suppress Pro-inflammatory Responses in Primary Murine Glia and Macrophages

African trypanosomes, such as Trypanosoma brucei (T. brucei), are protozoan parasites of the mammalian vasculature and central nervous system that are best known for causing fatal human sleeping sickness. As exclusively extracellular parasites, trypanosomes are subject to constant challenge from hos...

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Detalles Bibliográficos
Autores principales: Campbell, Nicole K., Williams, David G., Fitzgerald, Hannah K., Barry, Paul J., Cunningham, Clare C., Nolan, Derek P., Dunne, Aisling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749089/
https://www.ncbi.nlm.nih.gov/pubmed/31572363
http://dx.doi.org/10.3389/fimmu.2019.02137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749089/
https://www.ncbi.nlm.nih.gov/pubmed/31572363
http://dx.doi.org/10.3389/fimmu.2019.02137

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