Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis

TDP-43 is an RNA-binding protein that forms cytoplasmic aggregates in multiple neurodegenerative diseases. Although the loss of normal TDP-43 functions likely contributes to disease pathogenesis, the cell biological consequences of human TDP-43 depletion are not well understood. We, therefore, gener...

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Detalles Bibliográficos
Autores principales: Roczniak-Ferguson, Agnes, Ferguson, Shawn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749094/
https://www.ncbi.nlm.nih.gov/pubmed/31527135
http://dx.doi.org/10.26508/lsa.201900358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749094/
https://www.ncbi.nlm.nih.gov/pubmed/31527135
http://dx.doi.org/10.26508/lsa.201900358

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