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Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis
TDP-43 is an RNA-binding protein that forms cytoplasmic aggregates in multiple neurodegenerative diseases. Although the loss of normal TDP-43 functions likely contributes to disease pathogenesis, the cell biological consequences of human TDP-43 depletion are not well understood. We, therefore, gener...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Life Science Alliance LLC
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749094/ https://www.ncbi.nlm.nih.gov/pubmed/31527135 http://dx.doi.org/10.26508/lsa.201900358 |