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N-Glycosylation Site Analysis of Citrullinated Antigen-Specific B-Cell Receptors Indicates Alternative Selection Pathways During Autoreactive B-Cell Development

Many autoimmune diseases are hallmarked by autoreactive B and plasma cell responses that are directly or indirectly involved in disease pathogenesis. These B-cell responses show large variability between diseases, both in terms of the secreted autoantibody repertoire and the dynamics and characteris...

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Detalles Bibliográficos
Autores principales: Vergroesen, Rochelle D., Slot, Linda M., van Schaik, Barbera D. C., Koning, Marvyn T., Rispens, Theo, van Kampen, Antoine H. C., Toes, René E. M., Scherer, Hans U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749139/
https://www.ncbi.nlm.nih.gov/pubmed/31572358
http://dx.doi.org/10.3389/fimmu.2019.02092