Hybrids of Cinchona Alkaloids and Bile Acids as Antiparasitic Agents Against Trypanosoma cruzi

The current chemotherapy of Chagas disease needs to be urgently improved. With this aim, a series of 16 hybrids of Cinchona alkaloids and bile acids were prepared by functionalization at position C-2 of the quinoline nucleus by a radical attack of a norcholane substituent via a Barton–Zard decarboxy...

Descripción completa

Detalles Bibliográficos
Autores principales: Musikant, Daniel, Leverrier, Aurélie, Bernal, Diana, Ferri, Gabriel, Palermo, Jorge A., Edreira, Martin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749325/
https://www.ncbi.nlm.nih.gov/pubmed/31480402
http://dx.doi.org/10.3390/molecules24173168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749325/
https://www.ncbi.nlm.nih.gov/pubmed/31480402
http://dx.doi.org/10.3390/molecules24173168

Ejemplares similares