Probing the Effects of Pyrimidine Functional Group Switches on Acyclic Fleximer Analogues for Antiviral Activity

Due to their ability to inhibit viral DNA or RNA replication, nucleoside analogues have been used for decades as potent antiviral therapeutics. However, one of the major limitations of nucleoside analogues is the development of antiviral resistance. In that regard, flexible nucleoside analogues know...

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Detalles Bibliográficos
Autores principales: Yates, Mary K., Chatterjee, Payel, Flint, Mike, Arefeayne, Yafet, Makuc, Damjan, Plavec, Janez, Spiropoulou, Christina F., Seley-Radtke, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749450/
https://www.ncbi.nlm.nih.gov/pubmed/31480658
http://dx.doi.org/10.3390/molecules24173184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749450/
https://www.ncbi.nlm.nih.gov/pubmed/31480658
http://dx.doi.org/10.3390/molecules24173184

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