Cargando…

Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection

BACKGROUND: Anaemia is a major consequence of malaria, caused by the removal of both infected and uninfected red blood cells (RBCs) from the circulation. Complement activation and reduced expression of complement regulatory proteins (CRPs) on RBCs are an important pathogenic mechanism in severe mala...

Descripción completa

Detalles Bibliográficos
Autores principales: Oyong, Damian A., Loughland, Jessica R., SheelaNair, Arya, Andrew, Dean, Rivera, Fabian D. L., Piera, Kim A., William, Timothy, Grigg, Matthew J., Barber, Bridget E., Haque, Ashraful, Engwerda, Christian R., McCarthy, James S., Anstey, Nicholas M., Boyle, Michelle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749675/
https://www.ncbi.nlm.nih.gov/pubmed/31533836
http://dx.doi.org/10.1186/s12936-019-2962-0