Cargando…
Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection
BACKGROUND: Anaemia is a major consequence of malaria, caused by the removal of both infected and uninfected red blood cells (RBCs) from the circulation. Complement activation and reduced expression of complement regulatory proteins (CRPs) on RBCs are an important pathogenic mechanism in severe mala...
Autores principales: | Oyong, Damian A., Loughland, Jessica R., SheelaNair, Arya, Andrew, Dean, Rivera, Fabian D. L., Piera, Kim A., William, Timothy, Grigg, Matthew J., Barber, Bridget E., Haque, Ashraful, Engwerda, Christian R., McCarthy, James S., Anstey, Nicholas M., Boyle, Michelle J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749675/ https://www.ncbi.nlm.nih.gov/pubmed/31533836 http://dx.doi.org/10.1186/s12936-019-2962-0 |
Ejemplares similares
-
Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection
por: Loughland, Jessica R, et al.
Publicado: (2020) -
Reduced circulating dendritic cells in acute Plasmodium knowlesi and Plasmodium falciparum malaria despite elevated plasma Flt3 ligand levels
por: Loughland, Jessica R., et al.
Publicado: (2021) -
Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets
por: Dooley, Nicholas L., et al.
Publicado: (2023) -
Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation
por: Loughland, Jessica R., et al.
Publicado: (2017) -
Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection
por: Montes de Oca, Marcela, et al.
Publicado: (2016)