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Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

The heterogeneous nature of inflammatory bowel disease (IBD) presents challenges, particularly when choosing therapy. Activation of the NF-κB transcription factor is a highly regulated, dynamic event in IBD pathogenesis. Using a lentivirus approach, NF-κB-regulated luciferase was expressed in patien...

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Detalles Bibliográficos
Autores principales: Papoutsopoulou, Stamatia, Burkitt, Michael D., Bergey, François, England, Hazel, Hough, Rachael, Schmidt, Lorraine, Spiller, David G., White, Michael H. R., Paszek, Pawel, Jackson, Dean A., Martins Dos Santos, Vitor A. P., Sellge, Gernot, Pritchard, D. Mark, Campbell, Barry J., Müller, Werner, Probert, Chris S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749845/
https://www.ncbi.nlm.nih.gov/pubmed/31572379
http://dx.doi.org/10.3389/fimmu.2019.02168