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Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients
The heterogeneous nature of inflammatory bowel disease (IBD) presents challenges, particularly when choosing therapy. Activation of the NF-κB transcription factor is a highly regulated, dynamic event in IBD pathogenesis. Using a lentivirus approach, NF-κB-regulated luciferase was expressed in patien...
Autores principales: | Papoutsopoulou, Stamatia, Burkitt, Michael D., Bergey, François, England, Hazel, Hough, Rachael, Schmidt, Lorraine, Spiller, David G., White, Michael H. R., Paszek, Pawel, Jackson, Dean A., Martins Dos Santos, Vitor A. P., Sellge, Gernot, Pritchard, D. Mark, Campbell, Barry J., Müller, Werner, Probert, Chris S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749845/ https://www.ncbi.nlm.nih.gov/pubmed/31572379 http://dx.doi.org/10.3389/fimmu.2019.02168 |
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